一名男子被诊断患有罕见的脑部梅毒

一名男子被诊断患有罕见的脑部梅毒

A man was diagnosed with a syphilis infection in the brain, known as neurosyphilis, after he struggled to walk and talk normally for months, according to a recent case report.

根据最近的一份病例报告，一名男子在数月努力正常行走和说话之后，被诊断为脑部梅毒感染，也称神经梅毒。

The 50-year-old man’s case was detailed in the British Medical Journal Case Reports (BMJ). Doctors did not identify the man.

英国医学杂志《病例报告》(BMJ)详细报道了这名50岁男子的病例。医生没有指出这名男子的身份。

Three months before he sought treatment, the man reportedly lost his coordination and “developed tremors and uncontrolled eye movements,” according to the Daily Mail, which reviewed the report. He also had trouble speaking properly.

据英国《每日邮报》报道，该男子在接受治疗前三个月失去了协调性，“出现颤抖和无法控制的眼球运动”。他说话也有问题。

A brain MRI later revealed the man — who denied “high-risk sexual exposure or any previous history of genital infections or ulcers,” doctors wrote in the report — had damage to his cerebellum, the part of the brain that controls balance and speech, among other things.

随后的脑部核磁共振成像显示，这名男子的小脑受到了损伤，小脑是大脑中控制平衡和说话等功能的部分。医生在报告中写道，“这名男子否认自己有高风险的性接触，也否认曾有过生殖器感染或溃疡的病史”。

The man’s case of ataxia, which “describes a lack of muscle control or coordination of voluntary movements,” according to the Mayo Clinic, was also connected to the damage found in his cerebellum.

根据梅奥诊所的说法，这名男子的共济失调是由于缺乏肌肉控制或自主运动的协调性，因此与他小脑的损伤有关。

Further tests revealed the man was positive for Treponema pallidum, a type of bacteria that causes syphilis — a sexually transmitted infection that first appears as a small, painless sore.

进一步的测试显示，这名男子对梅毒螺旋体呈阳性反应。梅毒是一种引起梅毒的细菌，最初表现为一种小型无痛性感染。

Doctors determined he had neurosyphilis, a rare infection that typically occurs if an initial syphilis infection is left untreated.

医生诊断他患有神经梅毒，这是一种罕见的感染，通常发生在最初的梅毒感染不治疗的情况下。

“Neurosyphilis tends to develop about 10 to 20 years after the initial infection with the bacterium. Having HIV and untreated syphilis are major risk factors for neurosyphilis,” per Healthline.

“神经梅毒倾向于在最初感染这种细菌10到20年后发展。感染艾滋病毒和未经治疗的梅毒是神经梅毒的主要危险因素。”

There are five different forms of neurosyphilis — asymptomatic, meningeal, meningovascular, general paresis and tabes dorsalis — but, according to doctors who treated the man, he did not fall into any of those categories and did not exhibit any of the more common signs, such as nausea, vomiting or a stiff neck.

有五种不同形式的神经性梅毒：无症状、脑膜、脑膜血管、全身轻瘫和背侧平滑肌，但根据治疗该男子的医生所说，他不属于上述任何一类，也没有表现出任何更常见的症状，如恶心、呕吐、或者脖子僵硬。

The man was treated with antibiotics for two weeks and also underwent physiotherapy. He eventually recovered and relearned how to walk properly, doctors said.

这名男子接受了两周的抗生素治疗，还接受了理疗。医生说，他最终康复并重新学会了正确走路。