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科学家能让老鼠重返青春了

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2022年03月22日

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Researchers in the US treated healthy mice with a form of gene therapy that refreshed older cells, making the animals more youthful according to biological markers that are used to measure the effects of aging.
美国研究人员对健康老鼠实施了一种更新老化细胞的基因疗法并获得成功,通过生物标记法他们测出这些老鼠变年轻了。

The findings will fuel interest in radical new therapies that aim to slow or reverse the aging process as a means of tackling age-related diseases such as cancer, brittle bones and Alzheimer’s.
这一发现会点燃人们对以延缓或逆转衰老为目标的激进新疗法的兴趣,这种疗法可以用来治疗癌症、骨质疏松和老年痴呆症等老年常见疾病。


The scientists drew on previous work by the Japanese Nobel laureate Prof Shinya Yamanaka, who showed that a mixture of four molecules – known as Yamanaka factors – can rewind adult cells into youthful stem cells that are capable of forming almost any tissue in the body.
美国科学家的这一疗法借鉴了日本诺贝尔奖得主山中伸弥教授先前的研究成果。山中伸弥向世人展示,被称为“山中因子”的四种分子组合在一起可以让成人细胞逆生长为年轻的干细胞,而干细胞可以分化成人体的任何组织。


The US team found that mice who received Yamanaka factors for several months resembled younger animals in many ways, with their skin and kidneys in particular showing signs of rejuvenation.
美国团队发现,连续数月注射山中因子的老鼠在很多方面都变得像年轻老鼠,皮肤和肾脏的回春迹象尤为明显。
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